| CAS No.: | 10212-25-6 |
|---|---|
| Formula: | C9h12cln3o4 |
| EINECS: | 696-656-6 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Industrial |
| Samples: |
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| Customization: |
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Cyclocytidine hydrochloride is white acicular crystal or crystalline powder. No odor; It is easily soluble in water, slightly soluble in methanol and ethanol, and almost insoluble in ethyl ether, benzene and chloroform. It is effective for all types of acute leukemia and meningeal leukemia.
Specification
| Items | Specification | Results |
Appearance |
White crystalline or white powder |
Conforms |
Solubility |
Dissolve in water |
Conforms |
Identification(HPLC) |
. The retention time of the main peak in the sample solution should match the retention time of the main peak in the standard solution obtained in the test of the relevant substance. |
Conforms |
Loss on drying |
≤ 1.0% | 0.52% |
Ignition residue |
≤ 0.5% | 0.16% |
Specific rotation |
-19°~ -24° | -20° |
Related substances |
.Individual impurity: ≤ 0.5% .Total impurities: ≤ 2.0% |
0.24% 0.63% |
Identification |
98.0% ~ 102.0% | 99.46% |
Application and Function
Antitumor drugs. Adverse reactions are similar to cytarabine, but less severe. It has myelosuppressive effect. Leukopenia and thrombocytopenia. Parotid pain often occurs when the dosage is large, and local cold compress can alleviate the pain. Sometimes salivation can be seen in Chemicalbook, sometimes postural hypotension, conjunctival congestion, nasal mucosal swelling, individual patients appear headache, rash, and occasionally cause transient pulmonary inflammation. The blood should be examined strictly during the treatment.
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