APIs Calcium Folinatc Antidote 6035-45-6
Product Description
Mainly used as an antidote to folate antagonists (such as methotrexate, pyrimethamine and trimethoprim, etc.), calcium leucovorin is often used clinically to pre-prevent serious toxic effects
Specification
Inspection |
PH |
PH6.8-8.0 PH should be 6.8-8.0 |
7.0 |
|
Single impurity |
1.0% No more than 1.0% |
0.13% |
|
Total impurities |
2.5% No more than 2.5% |
0.68% |
|
Residual solvent |
|
0.3% No more than 0.3% |
Not detected |
|
|
|
1.0% No more than 1.0% |
0.07% |
|
Water |
16.0% Not more than 16.0% |
13.4% |
|
Heavy metal |
No more than 50 parts per million |
Conforms |
Content |
, C20H21CaN7O795.0%-102.0%. According to anhydrous matter, the content of C20H21CaN7O7 should be 95.0%-102.0%. |
100.2% |
Application and Function:
1. Mainly used as an antidote to folate antagonists (such as methotrexate, pyrimethamine and trimethoprim, etc.), calcium leucovorin is often used clinically to pre-prevent serious toxic effects caused by large doses or excessive treatment of methotrexate. 2, for folic acid treatment of the following diseases, such as oral diarrhea, protein-energy malnutrition (malnutrition), pregnancy or infancy caused by megaloblastic anemia is not effective. 3, as an adjunct treatment for colon cancer and rectal cancer. 4. Combined with 5-FU, it is used to treat digestive tract tumors or other 5-FU-sensitive tumors. 5, used in children leukemia, lymphoma and osteosarcoma and other large dose MTX treatment rescue
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Package :
25KGS/drum , n/a ,or upon customers' request.
Carton size : 40*45*60cm
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